The Integrative Health Podcast with Dr. Jen

How Mold and Mycotoxins Impact Hormones

Dr. Jen Episode 139

In this episode of the Integrative Health Podcast, Dr. Jen dives deep into the often-overlooked connection between mold exposure, mycotoxins, and hormone dysfunction—especially for women in perimenopause and midlife.

Dr. Jen explains why clean eating, supplements, and even hormone replacement therapy may fail when environmental toxins like mold are driving estrogen dominance, chronic fatigue, anxiety, weight gain, and histamine intolerance. She breaks down how fat-soluble mycotoxins interfere with liver detoxification, mitochondrial energy production, immune regulation, and nervous system balance.

This conversation explores the concept of the “perimenopause storm,” where declining hormonal resilience combined with mold exposure amplifies symptoms such as brain fog, heavy cycles, mood changes, and stubborn weight gain. Dr. Jen also issues an important warning about rapid weight loss and GLP-1 medications in mold-toxic individuals, emphasizing the dangers of mobilizing stored toxins without proper drainage.

Most importantly, Dr. Jen outlines a safer path to healing—focusing on nervous system regulation, environmental awareness, and gentle detoxification rather than aggressive protocols. If you feel stuck, reactive, or inflamed despite doing “all the right things,” this episode may reveal the missing piece.


Dr. Jen explains how mold and mycotoxin exposure disrupt hormones, drive estrogen dominance, impact perimenopause, affect the nervous system, and why detox must start with safety and environment.

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